Highly Selective PPARα (Peroxisome Proliferator‐Activated Receptor α) Agonist Pemafibrate Inhibits Stent Inflammation and Restenosis Assessed by Multimodality Molecular‐Microstructural Imaging

BACKGROUND: New pharmacological approaches are needed to prevent stent restenosis. This study tested the hypothesis that pemafibrate, a novel clinical selective PPARα (peroxisome proliferator‐activated receptor α) agonist, suppresses coronary stent‐induced arterial inflammation and neointimal hyperp...

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Detalles Bibliográficos
Autores principales: Iwata, Hiroshi, Osborn, Eric A., Ughi, Giovanni J., Murakami, Kentaro, Goettsch, Claudia, Hutcheson, Joshua D., Mauskapf, Adam, Mattson, Peter C., Libby, Peter, Singh, Sasha A., Matamalas, Joan, Aikawa, Elena, Tearney, Guillermo J., Aikawa, Masanori, Jaffer, Farouc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751880/
https://www.ncbi.nlm.nih.gov/pubmed/34632804
http://dx.doi.org/10.1161/JAHA.121.020834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751880/
https://www.ncbi.nlm.nih.gov/pubmed/34632804
http://dx.doi.org/10.1161/JAHA.121.020834

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