Evaluation of Xa inhibitors as potential inhibitors of the SARS-CoV-2 Mpro protease

Based on previous large-scale in silico screening several factor Xa inhibitors were proposed to potentially inhibit SARS-CoV-2 M(pro). In addition to their known anticoagulants activity this potential inhibition could have an additional therapeutic effect on patients with COVID-19 disease. In this s...

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Detalles Bibliográficos
Autores principales: Papaj, Katarzyna, Spychalska, Patrycja, Kapica, Patryk, Fischer, André, Nowak, Jakub, Bzówka, Maria, Sellner, Manuel, Lill, Markus A., Smieško, Martin, Góra, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752003/
https://www.ncbi.nlm.nih.gov/pubmed/35015795
http://dx.doi.org/10.1371/journal.pone.0262482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752003/
https://www.ncbi.nlm.nih.gov/pubmed/35015795
http://dx.doi.org/10.1371/journal.pone.0262482

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