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Preclinical evidence for mitochondrial DNA as a potential blood biomarker for chemotherapy-induced peripheral neuropathy

Chemotherapy-induced peripheral neuropathy (CIPN) is a serious dose-limiting side effect of several first-line chemotherapeutic agents including paclitaxel, oxaliplatin and bortezomib, for which no predictive marker is currently available. We have previously shown that mitochondrial dysfunction is a...

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Detalles Bibliográficos
Autores principales: Trecarichi, Annalisa, Duggett, Natalie A., Granat, Lucy, Lo, Samantha, Malik, Afshan N., Zuliani-Álvarez, Lorena, Flatters, Sarah J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752024/
https://www.ncbi.nlm.nih.gov/pubmed/35015774
http://dx.doi.org/10.1371/journal.pone.0262544