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Aging is associated with increased brain iron through cortex-derived hepcidin expression

Iron is an essential molecule for biological processes, but its accumulation can lead to oxidative stress and cellular death. Due to its oxidative effects, iron accumulation is implicated in the process of aging and neurodegenerative diseases. However, the mechanism for this increase in iron with ag...

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Detalles Bibliográficos
Autores principales: Sato, Tatsuya, Shapiro, Jason Solomon, Chang, Hsiang-Chun, Miller, Richard A, Ardehali, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752087/
https://www.ncbi.nlm.nih.gov/pubmed/35014607
http://dx.doi.org/10.7554/eLife.73456