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Pharmacokinetic modeling of morphine and its glucuronides: Comparison of nebulization versus intravenous route in healthy volunteers

Intravenous (i.v.) morphine is a safe, robust, and recommended treatment for severe pain using the titration principle. Despite its high efficacy, it is impacted by organizational constraints related to venous access. Nebulized (NEB) morphine may represent an alternative for titration but pharmacoki...

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Detalles Bibliográficos
Autores principales: Duflot, Thomas, Pereira, Tony, Tavolacci, Marie‐Pierre, Joannidès, Robinson, Aubrun, Frédéric, Lamoureux, Fabien, Lvovschi, Virginie Eve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752103/
https://www.ncbi.nlm.nih.gov/pubmed/34842366
http://dx.doi.org/10.1002/psp4.12735