Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies

Cilia formation is essential for human life. One of the earliest events in the ciliogenesis program is the recruitment of tau-tubulin kinase 2 (TTBK2) by the centriole distal appendage component CEP164. Due to the lack of high-resolution structural information on this complex, it is unclear how it i...

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Detalles Bibliográficos
Autores principales: Rosa e Silva, Ivan, Binó, Lucia, Johnson, Christopher M., Rutherford, Trevor J., Neuhaus, David, Andreeva, Antonina, Čajánek, Lukáš, van Breugel, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752127/
https://www.ncbi.nlm.nih.gov/pubmed/34499853
http://dx.doi.org/10.1016/j.str.2021.08.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752127/
https://www.ncbi.nlm.nih.gov/pubmed/34499853
http://dx.doi.org/10.1016/j.str.2021.08.007

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