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Toxoplasma-proximal and distal control by GBPs in human macrophages

Human guanylate binding proteins (GBPs) are key players of interferon–gamma (IFNγ)-induced cell intrinsic defense mechanisms targeting intracellular pathogens. In this study, we combine the well-established Toxoplasmagondii infection model with three in vitro macrophage culture systems to delineate...

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Detalles Bibliográficos
Autores principales: Fisch, Daniel, Clough, Barbara, Khan, Rabia, Healy, Lyn, Frickel, Eva-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752258/
https://www.ncbi.nlm.nih.gov/pubmed/34931666
http://dx.doi.org/10.1093/femspd/ftab058