Genetic deletion of p66shc and/or cyclophilin D results in decreased pulmonary vascular tone

AIMS: The pulmonary vascular tone and hypoxia-induced alterations of the pulmonary vasculature may be regulated by the mitochondrial membrane permeability transition pore (mPTP) that controls mitochondrial calcium load and apoptosis. We thus investigated, if the mitochondrial proteins p66shc and cyc...

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Detalles Bibliográficos
Autores principales: Gierhardt, Mareike, Pak, Oleg, Sydykov, Akylbek, Kraut, Simone, Schäffer, Julia, Garcia, Claudia, Veith, Christine, Zeidan, Esraa M, Brosien, Monika, Quanz, Karin, Esfandiary, Azadeh, Saraji, Alireza, Hadzic, Stefan, Kojonazarov, Baktybek, Wilhelm, Jochen, Ghofrani, Hossein A, Schermuly, Ralph T, Seeger, Werner, Grimminger, Friedrich, Herden, Christiane, Schulz, Rainer, Weissmann, Norbert, Heger, Jacqueline, Sommer, Natascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752355/
https://www.ncbi.nlm.nih.gov/pubmed/33119054
http://dx.doi.org/10.1093/cvr/cvaa310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752355/
https://www.ncbi.nlm.nih.gov/pubmed/33119054
http://dx.doi.org/10.1093/cvr/cvaa310

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