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Atrial nitroso-redox balance and refractoriness following on-pump cardiac surgery: a randomized trial of atorvastatin

AIMS: Systemic inflammation and increased activity of atrial NOX2-containing NADPH oxidases have been associated with the new onset of atrial fibrillation (AF) after cardiac surgery. In addition to lowering LDL-cholesterol, statins exert rapid anti-inflammatory and antioxidant effects, the clinical...

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Detalles Bibliográficos
Autores principales: Jayaram, Raja, Jones, Michael, Reilly, Svetlana, Crabtree, Mark J, Pal, Nikhil, Goodfellow, Nicola, Nahar, Keshav, Simon, Jillian, Carnicer, Ricardo, DeSilva, Ravi, Ratnatunga, Chandana, Petrou, Mario, Sayeed, Rana, Roalfe, Andrea, Channon, Keith M, Bashir, Yaver, Betts, Timothy, Hill, Michael, Casadei, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752359/
https://www.ncbi.nlm.nih.gov/pubmed/33098411
http://dx.doi.org/10.1093/cvr/cvaa302