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G protein-coupled receptor kinase 5 (GRK5) contributes to impaired cardiac function and immune cell recruitment in post-ischemic heart failure

AIMS : Myocardial infarction (MI) is the most common cause of heart failure (HF) worldwide. G protein-coupled receptor kinase 5 (GRK5) is upregulated in failing human myocardium and promotes maladaptive cardiac hypertrophy in animal models. However, the role of GRK5 in ischemic heart disease is stil...

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Detalles Bibliográficos
Autores principales: de Lucia, Claudio, Grisanti, Laurel A, Borghetti, Giulia, Piedepalumbo, Michela, Ibetti, Jessica, Lucchese, Anna Maria, Barr, Eric W, Roy, Rajika, Okyere, Ama Dedo, Murphy, Haley Christine, Gao, Erhe, Rengo, Giuseppe, Houser, Steven R, Tilley, Douglas G, Koch, Walter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752360/
https://www.ncbi.nlm.nih.gov/pubmed/33560342
http://dx.doi.org/10.1093/cvr/cvab044