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A Drug–Drug Interaction Study to Investigate the Effect of Nintedanib on the Pharmacokinetics of Microgynon (Ethinylestradiol and Levonorgestrel) in Female Patients with Systemic Sclerosis-Associated Interstitial Lung Disease

BACKGROUND AND OBJECTIVES: Nintedanib is a tyrosine kinase inhibitor approved for the treatment of systemic sclerosis-associated interstitial lung disease (SSc-ILD), idiopathic pulmonary fibrosis, and other chronic fibrosing ILDs with a progressive phenotype. As nintedanib may cause foetal harm, pat...

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Detalles Bibliográficos
Autores principales: Vonk, Madelon C., Guillén-Del-Castillo, Alfredo, Kreuter, Michael, Avis, Mandy, Marzin, Kristell, Mack, Salome R., Wind, Sven, Gahlemann, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752527/
https://www.ncbi.nlm.nih.gov/pubmed/34664183
http://dx.doi.org/10.1007/s13318-021-00728-7