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Esc peptides as novel potentiators of defective cystic fibrosis transmembrane conductance regulator: an unprecedented property of antimicrobial peptides

Mutations in the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) protein lead to persistent lung bacterial infections, mainly due to Pseudomonas aeruginosa, causing loss of respiratory function and finally death of people affected by CF. Unfortunately, even in the era of CFTR modulat...

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Detalles Bibliográficos
Autores principales: Ferrera, Loretta, Cappiello, Floriana, Loffredo, Maria Rosa, Puglisi, Elena, Casciaro, Bruno, Botta, Bruno, Galietta, Luis J. V., Mori, Mattia, Mangoni, Maria Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752549/
https://www.ncbi.nlm.nih.gov/pubmed/34971429
http://dx.doi.org/10.1007/s00018-021-04030-2