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Stabilization of SETD3 by deubiquitinase USP27 enhances cell proliferation and hepatocellular carcinoma progression

The histone methyltransferase SETD3 plays critical roles in various biological events, and its dysregulation is often associated with human diseases including cancer. However, the underlying regulatory mechanism remains elusive. Here, we reported that ubiquitin-specific peptidase 27 (USP27) promotes...

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Detalles Bibliográficos
Autores principales: Zou, Tingting, Wang, Yang, Dong, Ling, Che, Tiantian, Zhao, Huakan, Yan, Xiaohua, Lin, Zhenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752572/
https://www.ncbi.nlm.nih.gov/pubmed/35018513
http://dx.doi.org/10.1007/s00018-021-04118-9