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In COVID-19, NLRP3 inflammasome genetic variants are associated with critical disease and these effects are partly mediated by the sickness symptom complex: a nomothetic network approach

In coronavirus disease (COVID-19), the nucleotide-binding domain, leucine-rich repeat and pyrin domain-containing protein 3 (NLRP3) inflammasome is activated in response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Acute infections are accompanied by a sickness symptom...

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Detalles Bibliográficos
Autores principales: Maes, Michael, Tedesco Junior, Walton Luiz Del, Lozovoy, Marcell Alysson Batisti, Mori, Mayara Tiemi Enokida, Danelli, Tiago, Almeida, Elaine Regina Delicato de, Tejo, Alexandre Mestre, Tano, Zuleica Naomi, Reiche, Edna Maria Vissoci, Simão, Andréa Name Colado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752583/
https://www.ncbi.nlm.nih.gov/pubmed/35022530
http://dx.doi.org/10.1038/s41380-021-01431-4