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SARS-CoV-2 membrane protein causes the mitochondrial apoptosis and pulmonary edema via targeting BOK

Deaths caused by coronavirus disease 2019 (COVID-19) are largely due to the lungs edema resulting from the disruption of the lung alveolo-capillary barrier, induced by SARS-CoV-2-triggered pulmonary cell apoptosis. However, the molecular mechanism underlying the proapoptotic role of SARS-CoV-2 is st...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Wu, Yongjian, Meng, Xiaojun, Wang, Zhiying, Younis, Muhammad, Liu, Ye, Wang, Peihui, Huang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752586/
https://www.ncbi.nlm.nih.gov/pubmed/35022571
http://dx.doi.org/10.1038/s41418-022-00928-x