Targeting prooxidant MnSOD effect inhibits triple-negative breast cancer (TNBC) progression and M2 macrophage functions under the oncogenic stress

Triple-negative breast cancer (TNBC) has been shown with high mitochondrial oxidative phosphorylation and production of reactive oxygen species (ROS). MnSOD (SOD2) is a mitochondrial antioxidant defense that has been implicated in inhibition of human malignancies. However, the impact of MnSOD on imm...

Descripción completa

Detalles Bibliográficos
Autores principales: Al Haq, Aushia Tanzih, Tseng, Hong-Yu, Chen, Li-Mei, Wang, Chien-Chia, Hsu, Hsin-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752602/
https://www.ncbi.nlm.nih.gov/pubmed/35017469
http://dx.doi.org/10.1038/s41419-021-04486-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752602/
https://www.ncbi.nlm.nih.gov/pubmed/35017469
http://dx.doi.org/10.1038/s41419-021-04486-x

Ejemplares similares