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Robust differentiation of human enteroendocrine cells from intestinal stem cells

Enteroendocrine (EE) cells are the most abundant hormone-producing cells in humans and are critical regulators of energy homeostasis and gastrointestinal function. Challenges in converting human intestinal stem cells (ISCs) into functional EE cells, ex vivo, have limited progress in elucidating thei...

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Detalles Bibliográficos
Autores principales: Zeve, Daniel, Stas, Eric, de Sousa Casal, Joshua, Mannam, Prabhath, Qi, Wanshu, Yin, Xiaolei, Dubois, Sarah, Shah, Manasvi S., Syverson, Erin P., Hafner, Sophie, Karp, Jeffrey M., Carlone, Diana L., Ordovas-Montanes, Jose, Breault, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752608/
https://www.ncbi.nlm.nih.gov/pubmed/35017529
http://dx.doi.org/10.1038/s41467-021-27901-5