The interplay between membrane topology and mechanical forces in regulating T cell receptor activity

T cells are critically important for host defense against infections. T cell activation is specific because signal initiation requires T cell receptor (TCR) recognition of foreign antigen peptides presented by major histocompatibility complexes (pMHC) on antigen presenting cells (APCs). Recent advan...

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Detalles Bibliográficos
Autores principales: Al-Aghbar, Mohammad Ameen, Jainarayanan, Ashwin K., Dustin, Michael L., Roffler, Steve R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752658/
https://www.ncbi.nlm.nih.gov/pubmed/35017678
http://dx.doi.org/10.1038/s42003-021-02995-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752658/
https://www.ncbi.nlm.nih.gov/pubmed/35017678
http://dx.doi.org/10.1038/s42003-021-02995-1

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