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The interplay between membrane topology and mechanical forces in regulating T cell receptor activity
T cells are critically important for host defense against infections. T cell activation is specific because signal initiation requires T cell receptor (TCR) recognition of foreign antigen peptides presented by major histocompatibility complexes (pMHC) on antigen presenting cells (APCs). Recent advan...
Autores principales: | Al-Aghbar, Mohammad Ameen, Jainarayanan, Ashwin K., Dustin, Michael L., Roffler, Steve R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752658/ https://www.ncbi.nlm.nih.gov/pubmed/35017678 http://dx.doi.org/10.1038/s42003-021-02995-1 |
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