The metabolic stress-activated checkpoint LKB1-MARK3 axis acts as a tumor suppressor in high-grade serous ovarian carcinoma

High-grade serous ovarian carcinoma (HGSOC) is the most aggressive gynecological malignancy, resulting in approximately 70% of ovarian cancer deaths. However, it is still unclear how genetic dysregulations and biological processes generate the malignant subtype of HGSOC. Here we show that expression...

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Detalles Bibliográficos
Autores principales: Machino, Hidenori, Kaneko, Syuzo, Komatsu, Masaaki, Ikawa, Noriko, Asada, Ken, Nakato, Ryuichiro, Shozu, Kanto, Dozen, Ai, Sone, Kenbun, Yoshida, Hiroshi, Kato, Tomoyasu, Oda, Katsutoshi, Osuga, Yutaka, Fujii, Tomoyuki, von Keudell, Gottfried, Saloura, Vassiliki, Hamamoto, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752757/
https://www.ncbi.nlm.nih.gov/pubmed/35017636
http://dx.doi.org/10.1038/s42003-021-02992-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752757/
https://www.ncbi.nlm.nih.gov/pubmed/35017636
http://dx.doi.org/10.1038/s42003-021-02992-4

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