A GATA4-regulated secretory program suppresses tumors through recruitment of cytotoxic CD8 T cells

The GATA4 transcription factor acts as a master regulator of development of multiple tissues. GATA4 also acts in a distinct capacity to control a stress-inducible pro-inflammatory secretory program that is associated with senescence, a potent tumor suppression mechanism, but also operates in non-sen...

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Detalles Bibliográficos
Autores principales: Patel, Rupesh S., Romero, Rodrigo, Watson, Emma V., Liang, Anthony C., Burger, Megan, Westcott, Peter M. K., Mercer, Kim L., Bronson, Roderick T., Wooten, Eric C., Bhutkar, Arjun, Jacks, Tyler, Elledge, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752777/
https://www.ncbi.nlm.nih.gov/pubmed/35017504
http://dx.doi.org/10.1038/s41467-021-27731-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752777/
https://www.ncbi.nlm.nih.gov/pubmed/35017504
http://dx.doi.org/10.1038/s41467-021-27731-5

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