Cargando…
A GATA4-regulated secretory program suppresses tumors through recruitment of cytotoxic CD8 T cells
The GATA4 transcription factor acts as a master regulator of development of multiple tissues. GATA4 also acts in a distinct capacity to control a stress-inducible pro-inflammatory secretory program that is associated with senescence, a potent tumor suppression mechanism, but also operates in non-sen...
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752777/ https://www.ncbi.nlm.nih.gov/pubmed/35017504 http://dx.doi.org/10.1038/s41467-021-27731-5 |