C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis

Macrophages are integral to the pathogenesis of atherosclerosis, but the contribution of distinct macrophage subsets to disease remains poorly defined. Using single cell technologies and conditional ablation via a LysM(Cre+) Clec4a2(flox/DTR) mouse strain, we demonstrate that the expression of the C...

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Detalles Bibliográficos
Autores principales: Park, Inhye, Goddard, Michael E., Cole, Jennifer E., Zanin, Natacha, Lyytikäinen, Leo-Pekka, Lehtimäki, Terho, Andreakos, Evangelos, Feldmann, Marc, Udalova, Irina, Drozdov, Ignat, Monaco, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752790/
https://www.ncbi.nlm.nih.gov/pubmed/35017526
http://dx.doi.org/10.1038/s41467-021-27862-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752790/
https://www.ncbi.nlm.nih.gov/pubmed/35017526
http://dx.doi.org/10.1038/s41467-021-27862-9

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