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A novel cytokine consisting of the p40 and EBI3 subunits suppresses experimental autoimmune arthritis via reciprocal regulation of Th17 and Treg cells

OBJECTIVE: The interleukin (IL)-12 cytokine family is closely related to the development of T helper cells, which are responsible for autoimmune disease enhancement or suppression. IL-12 family members are generally heterodimers and share three α-subunits (p35, p19, and p28) and two β-subunits (p40...

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Detalles Bibliográficos
Autores principales: Lee, Seon-Yeong, Moon, Su-Jin, Moon, Young-Mee, Seo, Hyeon-Beom, Ryu, Jun-Geol, Lee, A Ram, Lee, Chae Rim, Kim, Da-Som, Her, Yang-Mi, Choi, Jeong Won, Kwok, Seung-Ki, Park, Sung-Hwan, Cho, Mi-La
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752814/
https://www.ncbi.nlm.nih.gov/pubmed/34782759
http://dx.doi.org/10.1038/s41423-021-00798-2