Berberine bridge enzyme-like oxidase-catalysed double bond isomerization acts as the pathway switch in cytochalasin synthesis

Cytochalasans (CYTs), as well as their polycyclic (pcCYTs) and polymerized (meCYTs) derivatives, constitute one of the largest families of fungal polyketide-nonribosomal peptide (PK-NRP) hybrid natural products. However, the mechanism of chemical conversion from mono-CYTs (moCYTs) to both pcCYTs and...

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Detalles Bibliográficos
Autores principales: Zhang, Jin-Mei, Liu, Xuan, Wei, Qian, Ma, Chuanteng, Li, Dehai, Zou, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752850/
https://www.ncbi.nlm.nih.gov/pubmed/35017571
http://dx.doi.org/10.1038/s41467-021-27931-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752850/
https://www.ncbi.nlm.nih.gov/pubmed/35017571
http://dx.doi.org/10.1038/s41467-021-27931-z

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