Cargando…

Matrix mechanics regulates epithelial defence against cancer by tuning dynamic localization of filamin

In epithelia, normal cells recognize and extrude out newly emerged transformed cells by competition. This process is the most fundamental epithelial defence against cancer, whose occasional failure promotes oncogenesis. However, little is known about what factors determine the success or failure of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pothapragada, Shilpa P., Gupta, Praver, Mukherjee, Soumi, Das, Tamal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752856/ https://www.ncbi.nlm.nih.gov/pubmed/35017535 http://dx.doi.org/10.1038/s41467-021-27896-z

Ejemplares similares

Mechanical imbalance between normal and cancer cells drives epithelial defense against cancer
por: Gupta, Praver, et al.
Publicado: (2023)

Localization of filamin in smooth muscle
Publicado: (1986)

Molecular Tuning of Filamin A Activities in the Context of Adhesion and Migration
por: Lamsoul, Isabelle, et al.
Publicado: (2020)

Structural mechanism of integrin inactivation by filamin
por: Liu, Jianmin, et al.
Publicado: (2015)

Wireless COVID-19 Telehealth: Leukocytes Encryption Guided by Amino Acid Matrix
por: Dey, Joydeep, et al.
Publicado: (2021)

Ureaplasma parvum infection alters filamin a dynamics in host cells
por: Allam, Ayman B, et al.
Publicado: (2011)

Periostin/Filamin-A: A Candidate Central Regulatory Axis for Valve Fibrogenesis and Matrix Compaction
por: Misra, Suniti, et al.
Publicado: (2021)

Documentation and Localization of Force-mediated Filamin A Domain Perturbations in Moving Cells
por: Nakamura, Fumihiko, et al.
Publicado: (2014)

G Protein-Coupled Receptors Directly Bind Filamin A with High Affinity and Promote Filamin Phosphorylation
por: Tirupula, Kalyan C., et al.
Publicado: (2015)

Migfilin and Filamin as Regulators of Integrin Activation in Endothelial Cells and Neutrophils
por: Das, Mitali, et al.
Publicado: (2011)

Structural basis of filamin A functions
por: Nakamura, Fumihiko, et al.
Publicado: (2007)

Filamin A modulates platelet function
por: Lopez, Jose J., et al.
Publicado: (2018)

Filamin A Regulates Cardiovascular Remodeling
por: Bandaru, Sashidar, et al.
Publicado: (2021)

Immunological Defence Mechanisms Against Biological Agents
por: Bologna, Mauro
Publicado: (2014)

Indications for a Novel Muscular Dystrophy Pathway: γ-Filamin, the Muscle-Specific Filamin Isoform, Interacts with Myotilin
por: van der Ven, Peter F.M., et al.
Publicado: (2000)

Ultrastructural localization of alpha-actinin and filamin in cultured cells with the immunogold staining (IGS) method
Publicado: (1984)

Our Defence against Smallpox
Publicado: (1920)

Our Defences against Smallpox
Publicado: (1919)

Local Defence System in Healthy Lungs
por: Lohova, Elizabeta, et al.
Publicado: (2021)

Molecular Basis of Filamin A-FilGAP Interaction and Its Impairment in Congenital Disorders Associated with Filamin A Mutations
por: Nakamura, Fumihiko, et al.
Publicado: (2009)

The first line of defence: insights into mechanisms and relevance of phagocytosis in epithelial cells
por: Günther, Juliane, et al.
Publicado: (2018)

Switching of filamin polypeptides during myogenesis in vitro
Publicado: (1983)

Evidence for the mechanosensor function of filamin in tissue development
por: Huelsmann, Sven, et al.
Publicado: (2016)

Filamin A increases aggressiveness of human neuroblastoma
por: Bandaru, Sashidar, et al.
Publicado: (2022)

Filamin C is Essential for mammalian myocardial integrity
por: Wu, Tongbin, et al.
Publicado: (2023)

Filamin A-Hinge Region 1-EGFP: A Novel Tool for Tracking the Cellular Functions of Filamin A in Real-Time
por: Planagumà, Jesús, et al.
Publicado: (2012)

Polarised epithelial monolayers of the gastric mucosa reveal insights into mucosal homeostasis and defence against infection
por: Boccellato, Francesco, et al.
Publicado: (2019)

Dynamic regulation of TREK1 gating by Polycystin 2 via a Filamin A-mediated cytoskeletal Mechanism
por: Li Fraine, Steven, et al.
Publicado: (2017)

RNase L Interacts with Filamin A To Regulate Actin Dynamics and Barrier Function for Viral Entry
por: Malathi, Krishnamurthy, et al.
Publicado: (2014)

Structural Interaction and Functional Regulation of Polycystin-2 by Filamin
por: Wang, Qian, et al.
Publicado: (2012)

Filamins Regulate Cell Spreading and Initiation of Cell Migration
por: Baldassarre, Massimiliano, et al.
Publicado: (2009)

Inhibition of Filamin-A Reduces Cancer Metastatic Potential
por: Jiang, Xi, et al.
Publicado: (2012)

Structure and Function of Filamin C in the Muscle Z-Disc
por: Mao, Zhenfeng, et al.
Publicado: (2020)

Biological roles of filamin a in prostate cancer cells
por: Li, Xue-Chao, et al.
Publicado: (2019)

BAY 41-2272 activates host defence against local and disseminated Candida albicans infections
por: Soeiro-Pereira, Paulo Vítor, et al.
Publicado: (2015)

Deciphering the role of polyphenol in defence mechanism against tea mosquito bug (Helopeltis theivora Waterhouse.) in cocoa (Theobroma cocoa L.)
por: K. S., Shilpa, et al.
Publicado: (2022)

Targeting filamin B induces tumor growth and metastasis via enhanced activity of matrix metalloproteinase-9 and secretion of VEGF-A
por: Bandaru, S, et al.
Publicado: (2014)

The collimation system: defence against beam loss
Publicado: (2013)

The Role of Mast Cells in the Defence against Pathogens
por: Urb, Mirjam, et al.
Publicado: (2012)

Foetal defence against cancer: a hypothesis
por: Yang, Hui-Tai, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_b8b12cmmor22p3me9n17q1ltrk