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Matrix mechanics regulates epithelial defence against cancer by tuning dynamic localization of filamin
In epithelia, normal cells recognize and extrude out newly emerged transformed cells by competition. This process is the most fundamental epithelial defence against cancer, whose occasional failure promotes oncogenesis. However, little is known about what factors determine the success or failure of...
Autores principales: | Pothapragada, Shilpa P., Gupta, Praver, Mukherjee, Soumi, Das, Tamal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752856/ https://www.ncbi.nlm.nih.gov/pubmed/35017535 http://dx.doi.org/10.1038/s41467-021-27896-z |
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