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Effects of the dipeptide L-glutamic acid-L-tryptophan on dermatitis in mice and human keratinocytes

Allergic contact dermatitis (ACD) and atopic dermatitis (AD) are inflammatory eczematous skin diseases caused by various factors. Here, we report that topical application of the dipeptide, L-glutamic acid-L-tryptophan (L-Glu-L-Trp), improved symptoms in both ACD and AD in mice. Using a mouse model o...

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Detalles Bibliográficos
Autores principales: Shibata, Shun, Kuwahara, Akiko, Sakaki-Yumoto, Masayo, Kawaguchi, Makoto, Ishii, Tsuyoshi, Honma, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752900/
https://www.ncbi.nlm.nih.gov/pubmed/35036609
http://dx.doi.org/10.1016/j.heliyon.2022.e08729