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miR-424/322 protects against abdominal aortic aneurysm formation by modulating the Smad2/3/runt-related transcription factor 2 axis

Rupture of abdominal aortic aneurysms (AAAs) is one of the leading causes of sudden death in the elderly population. The osteogenic transcription factor runt-related gene (RUNX) encodes multifunctional mediators of intracellular signal transduction pathways in vascular remodeling and inflammation. W...

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Detalles Bibliográficos
Autores principales: Tsai, Hsiao-Ya, Wang, Jen-Chun, Hsu, Yu-Juei, Chiu, Yi-Lin, Lin, Chih-Yuan, Lu, Cheng-Yo, Tsai, Shih-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752907/
https://www.ncbi.nlm.nih.gov/pubmed/35036072
http://dx.doi.org/10.1016/j.omtn.2021.12.028