Cargando…

miR-424/322 protects against abdominal aortic aneurysm formation by modulating the Smad2/3/runt-related transcription factor 2 axis

Rupture of abdominal aortic aneurysms (AAAs) is one of the leading causes of sudden death in the elderly population. The osteogenic transcription factor runt-related gene (RUNX) encodes multifunctional mediators of intracellular signal transduction pathways in vascular remodeling and inflammation. W...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsai, Hsiao-Ya, Wang, Jen-Chun, Hsu, Yu-Juei, Chiu, Yi-Lin, Lin, Chih-Yuan, Lu, Cheng-Yo, Tsai, Shih-Hung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752907/ https://www.ncbi.nlm.nih.gov/pubmed/35036072 http://dx.doi.org/10.1016/j.omtn.2021.12.028

Ejemplares similares

miR-424(322)-5p targets Ezh1 to inhibit the proliferation and differentiation of myoblasts : miR-424(322)-5p regulates the proliferation and differentiation of myoblasts
por: Yue, Yongqi, et al.
Publicado: (2023)

The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland
por: Llobet-Navas, David, et al.
Publicado: (2014)

Hyperuricemia exacerbates abdominal aortic aneurysm formation through the URAT1/ERK/MMP-9 signaling pathway
por: Wang, Jen-Chun, et al.
Publicado: (2023)

Inhibition of hypoxia inducible factor-1α attenuates abdominal aortic aneurysm progression through the down-regulation of matrix metalloproteinases
por: Tsai, Shih-Hung, et al.
Publicado: (2016)

miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy
por: Rodriguez-Barrueco, Ruth, et al.
Publicado: (2017)

Association between abdominal aortic aneurysms and alcohol-related diseases
por: Li, Ling-Yuan, et al.
Publicado: (2020)

miR-424(322) reverses chemoresistance via T-cell immune response activation by blocking the PD-L1 immune checkpoint
por: Xu, Shaohua, et al.
Publicado: (2016)

H19X-encoded miR-424(322)/-503 cluster: emerging roles in cell differentiation, proliferation, plasticity and metabolism
por: Wang, Fan, et al.
Publicado: (2018)

Reviewers BJCVS 32.2
Publicado: (2017)

The Association between Migraine and Abdominal Aortic Aneurysms: A Nationwide Population-Based Cohort Study
por: Lin, Jou-Yu, et al.
Publicado: (2021)

H19X‐encoded miR‐322(424)/miR‐503 regulates muscle mass by targeting translation initiation factors
por: Liang, Rui, et al.
Publicado: (2021)

MiR-424/TGIF2-Mediated Pro-Fibrogenic Responses in Oral Submucous Fibrosis
por: Chou, Ming-Yung, et al.
Publicado: (2023)

MiR-322/424 and -503 Are Induced during Muscle Differentiation and Promote Cell Cycle Quiescence and Differentiation by Down-Regulation of Cdc25A
por: Sarkar, Sukumar, et al.
Publicado: (2010)

PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response
por: Gupta, Ananya, et al.
Publicado: (2015)

Inhibition of Smurf2 translation by miR-322/503 modulates TGF-β/Smad2 signaling and intestinal epithelial homeostasis
por: Cao, Shan, et al.
Publicado: (2014)

Colonic manifestations of runt disease.
por: Singer, J. B., et al.
Publicado: (1966)

Performing different kinds of physical exercise differentially attenuates the genetic effects on obesity measures: Evidence from 18,424 Taiwan Biobank participants
por: Lin, Wan-Yu, et al.
Publicado: (2019)

Galectin-3 as a Biomarker for Stratifying Abdominal Aortic Aneurysm Size in a Taiwanese Population
por: Lu, Hsin-Ying, et al.
Publicado: (2021)

32.2 ABNORMALITIES OF SYNAPTIC PROTEOMES IN SCHIZOPHRENIA
por: Funk, Adam, et al.
Publicado: (2018)

Runx2 stimulates neoangiogenesis through the Runt domain in melanoma
por: Cecconi, Daniela, et al.
Publicado: (2019)

Toll-Like Receptor 4 Is Essential in the Development of Abdominal Aortic Aneurysm
por: Lai, Chao-Han, et al.
Publicado: (2016)

Transforming growth factor-β signaling pathway-associated genes SMAD2 and TGFBR2 are implicated in metabolic syndrome in a Taiwanese population
por: Lin, Eugene, et al.
Publicado: (2017)

Pharmacological Activation Of Aldehyde Dehydrogenase 2 Protects Against Heatstroke-Induced Acute Lung Injury by Modulating Oxidative Stress and Endothelial Dysfunction
por: Tsai, Hsiao-Ya, et al.
Publicado: (2021)

IMMUNOLOGIC INCOMPETENCE OF IMMUNOLOGICALLY RUNTED ANIMALS
por: Blaese, R. Michael, et al.
Publicado: (1964)

STUDIES ON THE IMMUNOTHERAPY OF RUNT DISEASE IN RATS
por: Silvers, Willys K., et al.
Publicado: (1969)

STUDIES ON THE RUNTING SYNDROME IN NEWBORN MICE
por: Siskind, Gregory W., et al.
Publicado: (1959)

Characterization of SMAD2 Activation in Human Thoracic Aortic Aneurysm
por: Fukuda, Hayato, et al.
Publicado: (2018)

THE PRODUCTION OF RUNT DISEASE IN RATS THYMECTOMIZED AT BIRTH
por: Aisenberg, Alan C., et al.
Publicado: (1962)

Primary aortoduodenal fistula associated with abdominal aortic aneurysm with presentation of gastrointestinal bleeding: a case report
por: Lin, Tzu-Chieh, et al.
Publicado: (2018)

Regulation and functional role of the Runt-related transcription factor-2 in pancreatic cancer
por: Kayed, H, et al.
Publicado: (2007)

New Insights into the Runt Domain of RUNX2 in Melanoma Cell Proliferation and Migration
por: Deiana, Michela, et al.
Publicado: (2018)

Publisher Correction: Runx2 stimulates neoangiogenesis through the Runt domain in melanoma
por: Cecconi, Daniela, et al.
Publicado: (2020)

S32.2 SARS — Future perspectives from past experiences
Publicado: (2005)

Dysregulated Kras/YY1/ZNF322A/Shh transcriptional axis enhances neo-angiogenesis to promote lung cancer progression
por: Lin, Che-Chung, et al.
Publicado: (2020)

Dipeptidyl Peptidase-4 Inhibitor Decreases Abdominal Aortic Aneurysm Formation through GLP-1-Dependent Monocytic Activity in Mice
por: Lu, Hsin Ying, et al.
Publicado: (2015)

LncRNA MBNL1-AS1 represses gastric cancer progression via the TGF-β pathway by modulating miR-424-5p/Smad7 axis
por: Su, Jiewen, et al.
Publicado: (2022)

Hereditary Hemorrhagic Telangiectasia with SMAD4 Mutations Is Associated with Fatty Degeneration of the Left Ventricle, Coronary Artery Aneurysm, and Abdominal Aortic Aneurysm
por: Inoguchi, Yasunori, et al.
Publicado: (2018)

Combination immunohistochemistry for SMAD4 and Runt-related transcription factor 3 may identify a favorable prognostic subgroup of pancreatic ductal adenocarcinomas
por: Lee, Yangkyu, et al.
Publicado: (2017)

Effects of runt-related transcription factor 2 (RUNX2) on the autophagy of rapamycin-treated osteoblasts
por: Ren, Cheng, et al.
Publicado: (2022)

MicroRNA-424 inhibits Akt3/E2F3 axis and tumor growth in hepatocellular carcinoma
por: Yang, Hao, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_rd05dia4lpm3b1finb5p83olbv