Improving LC-MS analysis of human milk B-vitamins by lactose removal

Our previously reported, first validated, UPLC-MS/MS-based simultaneous analysis of five human milk B-vitamins revealed severe matrix effects. High levels of endogenous lactose fouled the electrospray ionization source affecting the analysis. We evaluated solid-phase extraction (SPE), liquid–solid e...

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Detalles Bibliográficos
Autores principales: Hampel, Daniela, Shahab-Ferdows, Setareh, Newman, John W., Allen, Lindsay H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752959/
https://www.ncbi.nlm.nih.gov/pubmed/34628184
http://dx.doi.org/10.1016/j.jchromb.2021.122968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752959/
https://www.ncbi.nlm.nih.gov/pubmed/34628184
http://dx.doi.org/10.1016/j.jchromb.2021.122968

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