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Improving LC-MS analysis of human milk B-vitamins by lactose removal
Our previously reported, first validated, UPLC-MS/MS-based simultaneous analysis of five human milk B-vitamins revealed severe matrix effects. High levels of endogenous lactose fouled the electrospray ionization source affecting the analysis. We evaluated solid-phase extraction (SPE), liquid–solid e...
Autores principales: | Hampel, Daniela, Shahab-Ferdows, Setareh, Newman, John W., Allen, Lindsay H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752959/ https://www.ncbi.nlm.nih.gov/pubmed/34628184 http://dx.doi.org/10.1016/j.jchromb.2021.122968 |
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