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Age‐related decline in cortical inhibitory tone strengthens motor memory

Ageing disrupts the finely tuned excitation/inhibition balance (E:I) across cortex via a natural decline in inhibitory tone ([Formula: see text]-amino butyric acid, GABA), causing functional decrements. However, in young adults, experimentally lowering GABA in sensorimotor cortex enhances a specific...

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Detalles Bibliográficos
Autores principales: Petitet, Pierre, Spitz, Gershon, Emir, Uzay E., Johansen-Berg, Heidi, O’Shea, Jacinta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752967/
https://www.ncbi.nlm.nih.gov/pubmed/34728243
http://dx.doi.org/10.1016/j.neuroimage.2021.118681