Microsecond molecular dynamics simulations revealed the inhibitory potency of amiloride analogs against SARS-CoV-2 E viroporin

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encodes small envelope protein (E) that plays a major role in viral assembly, release, pathogenesis, and host inflammation. Previous studies demonstrated that pyrazine ring containing amiloride analogs inhibit this protein in different typ...

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Detalles Bibliográficos
Autores principales: Jaber, Abdullah All, Chowdhury, Zeshan Mahmud, Bhattacharjee, Arittra, Mourin, Muntahi, Keya, Chaman Ara, Bhuyan, Zaied Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752979/
https://www.ncbi.nlm.nih.gov/pubmed/35172476
http://dx.doi.org/10.5808/gi.21040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752979/
https://www.ncbi.nlm.nih.gov/pubmed/35172476
http://dx.doi.org/10.5808/gi.21040

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