Non-monotonic fibril surface occlusion by GFP tags from coarse-grained molecular simulations

The pathological growth of amyloid fibrils in neurons underlies the progression of neurodegenerative diseases including Alzheimer’s and Parkinson’s disease. Fibrils form when soluble monomers oligomerise in the cytoplasm. Their subsequent growth occurs via nucleated polymerization mechanisms involvi...

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Detalles Bibliográficos
Autores principales: Shillcock, Julian C., Hastings, Janna, Riguet, Nathan, Lashuel, Hilal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753129/
https://www.ncbi.nlm.nih.gov/pubmed/35070162
http://dx.doi.org/10.1016/j.csbj.2021.12.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753129/
https://www.ncbi.nlm.nih.gov/pubmed/35070162
http://dx.doi.org/10.1016/j.csbj.2021.12.017

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