Determination of MYD88(L265P) mutation fraction in IgM monoclonal gammopathies

We describe a novel method for the detection of MYD88(L265P) mutation using a competitive allele-specific polymerase chain reaction (Cast-PCR) assay. This assay has a sensitivity of 1 × 10(−3), is applicable in reactions containing very low amounts of DNA (as low as 20 pg), and allowed the detection...

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Detalles Bibliográficos
Autores principales: Bagratuni, Tina, Markou, Athina, Patseas, Dimitrios, Mavrianou-Koutsoukou, Nefeli, Aktypi, Foteini, Liacos, Christine Ivy, Sklirou, Aimilia D., Theodorakakou, Foteini, Ntanasis-Stathopoulos, Ioannis, Gavriatopoulou, Maria, Trougakos, Ioannis P., Lianidou, Evi, Terpos, Evangelos, Kastritis, Efstathios, Dimopoulos, Meletios A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753203/
https://www.ncbi.nlm.nih.gov/pubmed/34788399
http://dx.doi.org/10.1182/bloodadvances.2021005354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753203/
https://www.ncbi.nlm.nih.gov/pubmed/34788399
http://dx.doi.org/10.1182/bloodadvances.2021005354

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