Assessment of HLA-B genetic variation with an HLA-B leader tool and implications in clinical transplantation

Sequence variation in the HLA-B gene is critically linked to differential immune responses. A dimorphism at -21 of HLA-B exon 1 gives rise to leader peptides that are markers for risk of acute graft-versus-host disease, relapse, and mortality after unrelated donor and cord blood transplantation. To...

Descripción completa

Detalles Bibliográficos
Autores principales: Sajulga, Ray, Bolon, Yung-Tsi, Maiers, Martin J., Petersdorf, Effie W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753210/
https://www.ncbi.nlm.nih.gov/pubmed/34529780
http://dx.doi.org/10.1182/bloodadvances.2021004561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753210/
https://www.ncbi.nlm.nih.gov/pubmed/34529780
http://dx.doi.org/10.1182/bloodadvances.2021004561

Ejemplares similares