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An IDO1-related immune gene signature predicts overall survival in acute myeloid leukemia

The contribution of the bone marrow (BM) immune microenvironment to acute myeloid leukemia (AML) development is well-known, but its prognostic significance is still elusive. Indoleamine 2,3-dioxygenase 1 (IDO1), which is negatively regulated by the BIN1 proto-oncogene, is an interferon-γ-inducible m...

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Detalles Bibliográficos
Autores principales: Ragaini, Simone, Wagner, Sarah, Marconi, Giovanni, Parisi, Sarah, Sartor, Chiara, Nanni, Jacopo, Cristiano, Gianluca, Talami, Annalisa, Olivi, Matteo, Ocadlikova, Darina, Ciciarello, Marilena, Corradi, Giulia, Ottaviani, Emanuela, Papayannidis, Cristina, Paolini, Stefania, Vadakekolathu, Jayakumar, Cavo, Michele, Rutella, Sergio, Curti, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753212/
https://www.ncbi.nlm.nih.gov/pubmed/34535017
http://dx.doi.org/10.1182/bloodadvances.2021004878