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Inducible Sbds deletion impairs bone marrow niche capacity to engraft donor bone marrow after transplantation

Bone marrow (BM) niche-derived signals are critical for facilitating engraftment after hematopoietic stem cell (HSC) transplantation (HSCT). HSCT is required for restoration of hematopoiesis in patients with inherited BM failure syndromes (iBMFSs). Shwachman-Diamond syndrome (SDS) is a rare iBMFS as...

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Detalles Bibliográficos
Autores principales: Zha, Ji, Kunselman, Lori K., Xie, Hongbo M., Ennis, Brian, Shah, Yash B., Qin, Xia, Fan, Jian-Meng, Babushok, Daria V., Olson, Timothy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753223/
https://www.ncbi.nlm.nih.gov/pubmed/34625796
http://dx.doi.org/10.1182/bloodadvances.2021004640