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Vitexin Inhibits Gastric Cancer Growth and Metastasis through HMGB1-mediated Inactivation of the PI3K/AKT/mTOR/HIF-1α Signaling Pathway

PURPOSE: Gastric cancer (GC) has high morbidity and mortality and is a serious threat to public health. The flavonoid compound vitexin is known to exhibit anti-tumor activity. In this study, we explored the therapeutic potential of vitexin in GC and its underlying mechanism. MATERIALS AND METHODS: T...

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Detalles Bibliográficos
Autores principales: Zhou, Peng, Zheng, Zi-Han, Wan, Tao, Wu, Jie, Liao, Chuan-Wen, Sun, Xue-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Gastric Cancer Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753280/
https://www.ncbi.nlm.nih.gov/pubmed/35079445
http://dx.doi.org/10.5230/jgc.2021.21.e40