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IL-6-elafin genetically modified macrophages as a lung immunotherapeutic strategy against Pseudomonas aeruginosa infections

Pseudomonas aeruginosa (P.a) infections are a major public health issue in ventilator-associated pneumoniae, cystic fibrosis, and chronic obstructive pulmonary disease exacerbations. P.a is multidrug resistant, and there is an urgent need to develop new therapeutic approaches. Here, we evaluated the...

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Detalles Bibliográficos
Autores principales: Kheir, Saadé, Villeret, Bérengère, Garcia-Verdugo, Ignacio, Sallenave, Jean-Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753374/
https://www.ncbi.nlm.nih.gov/pubmed/34371178
http://dx.doi.org/10.1016/j.ymthe.2021.08.007