Immunologic constant of rejection signature is prognostic in soft-tissue sarcoma and refines the CINSARC signature

BACKGROUND: Soft-tissue sarcomas (STSs) are heterogeneous and aggressive tumors, with high metastatic risk. The immunologic constant of rejection (ICR) 20-gene signature is a signature of cytotoxic immune response. We hypothesized that ICR might improve the prognostic assessment of early-stage STS....

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Detalles Bibliográficos
Autores principales: Bertucci, Francois, Niziers, Vincent, de Nonneville, Alexandre, Finetti, Pascal, Mescam, Léna, Mir, Olivier, Italiano, Antoine, Le Cesne, Axel, Blay, Jean-Yves, Ceccarelli, Michele, Bedognetti, Davide, Birnbaum, Daniel, Mamessier, Emilie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753443/
https://www.ncbi.nlm.nih.gov/pubmed/35017155
http://dx.doi.org/10.1136/jitc-2021-003687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753443/
https://www.ncbi.nlm.nih.gov/pubmed/35017155
http://dx.doi.org/10.1136/jitc-2021-003687

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