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Role of airway smooth muscle cell phenotypes in airway tone and obstruction in guinea pig asthma model
BACKGROUND: Airway obstruction (AO) in asthma is driven by airway smooth muscle (ASM) contraction. AO can be induced extrinsically by direct stimulation of ASM with contractile agonists as histamine, or by indirect provocation with antigens as ovalbumin, while the airway tone is dependent on intrins...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753847/ https://www.ncbi.nlm.nih.gov/pubmed/35016714 http://dx.doi.org/10.1186/s13223-022-00645-7 |