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Role of airway smooth muscle cell phenotypes in airway tone and obstruction in guinea pig asthma model

BACKGROUND: Airway obstruction (AO) in asthma is driven by airway smooth muscle (ASM) contraction. AO can be induced extrinsically by direct stimulation of ASM with contractile agonists as histamine, or by indirect provocation with antigens as ovalbumin, while the airway tone is dependent on intrins...

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Detalles Bibliográficos
Autores principales: Álvarez-Santos, Mayra D., Álvarez-González, Marisol, Eslava-De-Jesus, Elizabeth, González-López, Angel, Pacheco-Alba, Ivonne, Pérez-Del-Valle, Yazmín, Rojas-Madrid, Rodrigo, Bazán-Perkins, Blanca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753847/
https://www.ncbi.nlm.nih.gov/pubmed/35016714
http://dx.doi.org/10.1186/s13223-022-00645-7