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Short-term starvation synergistically enhances cytotoxicity of Niraparib via Akt/mTOR signaling pathway in ovarian cancer therapy

BACKGROUND: Short-term starvation (STS) has gradually been confirmed as a treatment method that synergistically enhances the effect of chemotherapy on malignant tumours. In clinical applications, there are still some limitations of poly (ADP-ribose) polymerase inhibitors (PARPi), including understan...

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Detalles Bibliográficos
Autores principales: Zhi, Wang, Li, Suting, Wan, Yuting, Wu, Fuwen, Hong, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753877/
https://www.ncbi.nlm.nih.gov/pubmed/35016681
http://dx.doi.org/10.1186/s12935-022-02447-8