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Contribution of 3D genome topological domains to genetic risk of cancers: a genome-wide computational study
BACKGROUND: Genome-wide association studies have identified statistical associations between various diseases, including cancers, and a large number of single-nucleotide polymorphisms (SNPs). However, they provide no direct explanation of the mechanisms underlying the association. Based on the recen...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753905/ https://www.ncbi.nlm.nih.gov/pubmed/35016721 http://dx.doi.org/10.1186/s40246-022-00375-2 |