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Contribution of 3D genome topological domains to genetic risk of cancers: a genome-wide computational study

BACKGROUND: Genome-wide association studies have identified statistical associations between various diseases, including cancers, and a large number of single-nucleotide polymorphisms (SNPs). However, they provide no direct explanation of the mechanisms underlying the association. Based on the recen...

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Detalles Bibliográficos
Autores principales:	Jablonski, Kim Philipp, Carron, Leopold, Mozziconacci, Julien, Forné, Thierry, Hütt, Marc-Thorsten, Lesne, Annick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753905/ https://www.ncbi.nlm.nih.gov/pubmed/35016721 http://dx.doi.org/10.1186/s40246-022-00375-2

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