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Interaction of obesity polygenic score with lifestyle risk factors in an electronic health record biobank

BACKGROUND: Genetic and lifestyle factors have considerable effects on obesity and related diseases, yet their effects in a clinical cohort are unknown. This study in a patient biobank examined associations of a BMI polygenic risk score (PRS), and its interactions with lifestyle risk factors, with c...

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Detalles Bibliográficos
Autores principales: Dashti, Hassan S., Miranda, Nicole, Cade, Brian E., Huang, Tianyi, Redline, Susan, Karlson, Elizabeth W., Saxena, Richa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753909/
https://www.ncbi.nlm.nih.gov/pubmed/35016652
http://dx.doi.org/10.1186/s12916-021-02198-9