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Protein tyrosine phosphatase receptor-ζ1 deletion triggers defective heart morphogenesis in mice and zebrafish

Protein tyrosine phosphatase receptor-ζ1 (PTPRZ1) is a transmembrane tyrosine phosphatase receptor highly expressed in embryonic stem cells. In the present work, gene expression analyses of Ptprz1(−/−) and Ptprz1(+/+) mice endothelial cells and hearts pointed to an unidentified role of PTPRZ1 in hea...

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Detalles Bibliográficos
Autores principales: Katraki-Pavlou, Stamatiki, Kastana, Pinelopi, Bousis, Dimitris, Ntenekou, Despoina, Varela, Aimilia, Davos, Constantinos H., Nikou, Sophia, Papadaki, Eleni, Tsigkas, Grigorios, Athanasiadis, Emmanouil, Herradon, Gonzalo, Mikelis, Constantinos M., Beis, Dimitris, Papadimitriou, Evangelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754060/
https://www.ncbi.nlm.nih.gov/pubmed/34767486
http://dx.doi.org/10.1152/ajpheart.00400.2021