Jerveratrum-Type Steroidal Alkaloids Inhibit β-1,6-Glucan Biosynthesis in Fungal Cell Walls

The limited number of available effective agents necessitates the development of new antifungals. We report that jervine, a jerveratrum-type steroidal alkaloid isolated from Veratrum californicum, has antifungal activity. Phenotypic comparisons of cell wall mutants, K1 killer toxin susceptibility te...

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Detalles Bibliográficos
Autores principales: Kubo, Karen, Itto-Nakama, Kaori, Ohnuki, Shinsuke, Yashiroda, Yoko, Li, Sheena C., Kimura, Hiromi, Kawamura, Yumi, Shimamoto, Yasuhiro, Tominaga, Ken-Ichi, Yamanaka, Daisuke, Adachi, Yoshiyuki, Takashima, Shinichiro, Noda, Yoichi, Boone, Charles, Ohya, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754110/
https://www.ncbi.nlm.nih.gov/pubmed/35019680
http://dx.doi.org/10.1128/spectrum.00873-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754110/
https://www.ncbi.nlm.nih.gov/pubmed/35019680
http://dx.doi.org/10.1128/spectrum.00873-21

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