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Disruption of NBS1/MRN Complex Formation by E4orf3 Supports NF-κB That Licenses E1B55K-Deleted Adenovirus-Infected Cells to Accumulate DNA>4n

Cells increase their DNA content greater than the G2/M (DNA > 4n) phases along the path to cancer. The signals that support this increase in DNA content remain poorly understood. Cells infected with adenovirus (Ad) similarly develop DNA > 4n and share a need to bypass the DNA damage response (...

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Detalles Bibliográficos
Autores principales: Almuzaini, Nujud, Moore, Madison, Robert-Guroff, Marjorie, Thomas, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754114/
https://www.ncbi.nlm.nih.gov/pubmed/35019694
http://dx.doi.org/10.1128/spectrum.01881-21