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Emergence of a KPC-90 Variant that Confers Resistance to Ceftazidime-Avibactam in an ST463 Carbapenem-Resistant Pseudomonas aeruginosa Strain

Carbapenem-resistant Pseudomonas aeruginosa (CRPA) has become a serious challenge in the clinic. Recently, the prevalence of CRPA isolates carrying the bla(KPC-2) gene has been increasing in China. Ceftazidime-avibactam (CZA) has shown good efficacy against large portions of KPC-2-producing CRPA str...

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Detalles Bibliográficos
Autores principales: Tu, Yuexing, Wang, Dairong, Zhu, Yiwei, Li, Jiayan, Jiang, Yan, Wu, Wenhao, Li, Xi, Zhou, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754116/
https://www.ncbi.nlm.nih.gov/pubmed/35019766
http://dx.doi.org/10.1128/spectrum.01869-21